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Zometa

Zometa, manufactured by Novartis, is a common intravenous bisposphonate similar to Actonel, Aredia, Boniva, and Fosamax. It is prescribed to prevent bone loss, but has very serious side effects including the development of a condition known as Osteonecrosis of the Jaw (ONJ). ONJ causes the jaw bone to degenerate, resulting in serious and irreparable side effects including bone loss, pain, numbness, and exposed bone. Other side effects of Zometa include difficulty breathing, kidney problems and low levels of calcium.

Fast Facts

Name: Zometa
Generic: Zoledronic Acid
Manufacturer: Novartis
Date approved: 2001
Status: Prescription only
Approved uses: Treatment and prevention of bone loss
Off-Label uses: Anti-fracture uses; however, the anti-fracture properties of bisphosphonates such as Zometa have not been proven
Side effects: Osteonecrosis of the Jaw (ONJ), bone pain, tissue death, loose teeth, sore gums, bone loss, pain and numbness, difficulty breathing, bone fractures, joint disorders, dental problems, kidney problems
Related topics: Fosamax, Bisphosphonates, Boniva, Aredia, Actonel

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FDA Warns Dentists About Zometa Risks

Millions of cancer patients rely on bisphosphonate drug Zometa to help prevent cancer-related osteoporosis, bone breakage and pain related to bone metastases. But Zometa has come under fire in... read more

View the Zometa Main Articles page here


FDA Information Related to Zometa

Pediatric Exclusivity Determinations

CDER Priority Drug and Biologic Approvals in Calendar Year 2007

View the Zometa FDA Information page here


MSN Newsfeeds Related to Zometa

Duluth-based health system bans pharmaceutical logos

Musculoskeletal pain? Consider patient meds

View the Zometa MSN Newsfeeds page here


News Articles Related to Zometa

Odanacatib, An Investigational Cathepsin K Inhibitor, Reduced Markers Of Bone Turnover In Women With Breast Cancer And Bone Metastases

Influence of Musculoskeletal Conditions on Oral Health Among Older Adults - Health - redOrbit

View the Zometa News Articles page here


Patents Related to Zometa

Substituted alkanediphosphonic acids and pharmaceutical use

View the Zometa Patents page here


Wikipedia Entries Related to Zometa

Zoledronic acid

Novartis

View the Zometa Wikipedia Entries page here


Books Related to Zometa

Zoledronic acid protects bone in prostate cancer: the drug reduced the risk of skeletal complications in patients receiving androgen-deprivation therapy. : An article from: Internal Medicine News

Zoledronic acid sustains bone in breast ca patients.(Women's Health) : An article from: Family Practice News

View the Zometa Books page here

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